Scientific Programme

Day 1 – Friday, 29 March 2019

14:00-14:10 Opening
14:10-15:20 Plenary session / Congress Hall
14:1014:45 PL-1
Lajos Haracska
Engines of carcinogenesis; what determines the speed of mutagenesis?
14:4515:20 PL-2
Péter Lénárt
Unexpected functions of the actin cytoskeleton in meiotic divisions of oocytes
15:20-16:10 Tankó awards
15:20-15:45
TA-1
László Vigh
From thermosensor membranes to membrane lipid therapy
15:4516:10 TA-2
Ferenc Erdődi
Forty years with protein phosphatases: past, present and future
16:10-16:50 Coffee break
16:50-17:55 Cell differentiation & Signaling / Congress Hall
Chair: László Buday
Stem cells / Session Room Liget I.
Chair: András Nagy
16:5017:10 O-01
Gábor Bánhegyi
Ca2+ mobilization dependent reduction of the ER lumen is due to influx of cytosolic glutathione
O-05
András Nagy
Treating disease with organoids requires solutions for two major hurdles
17:10-17:25 O-02
Zoltán Kármán
Identification of novel substrates of the evolutionarily conserved PP4 phosphatase to better understand its role in mitosis
O-06
Nándor Nagy
Talpid3 regulates multiple aspects of neuromuscular patterning during gastrointestinal development in animal models and human
17:25-17:40 O-03
Gergő Kovács
Role of RYBP in balancing between early and late neural processes
O-07
Ádám Oszwald
Extracellular vesicles transmit epithelial growth factor activity in the intestinal epithelial stem cell niche
17:4017:55 O-04
Endre Kristóf
Functional characterization and gene expression patterns of human adipocytes from the neck support high thermogenic potential in the deep region
O-08
Annamária Nemes
Generating new human vascular smooth muscle cells from pluripotent stem cells
17:55-18:00 Technical break
18:00-18:45 Sponsored talks (companies) / Congress Hall
 
18:00-18:15 ST-1
ROCHE, Ádám Józsa
Roche Molecular Solutions in life science
 
18:15-18:30 ST-2
ZEISS, Gert Sonntag
Fast and Gentle 3D Superresolution
 
18:30-18:45 ST-3
ThermoFisher Scientific, Salvatore Conti
Ion GeneStudio S5 systems: New tools for further NGS pipelines by ThermoFisher Scientific
 
19:00-20:30 Welcome dinner
20:30-22:00 Poster discussion with drinks – Poster session I. (P001 – P114)
Jump to Poster session I.

 

Day 2 – Saturday, 30 March 2019

9:00-10:20 Developmental Genetics / Congress Hall
Chair: Rita Sinka
Plant biology / Session Room Liget I.
Chair: László Szabados
9:00-9:20 O-09
Alexander W. Bruce
Deciphering the nodal role of p38 family of mitogen-activated protein kinases (MAPKs) towards specifying primitive endoderm (PrE) fate in the inner cell mass (ICM) of late-blastocyst stage mouse pre-implantation embryo
O-14
László Szabados
Light control of salt-induced proline accumulation is mediated by ELONGATED HYPOCOTYL 5 in Arabidopsis
9:20-9:35 O-10
Viktor Honti

Analysis of sessile tissue integrity and function in Drosophila melanogaster
O-15
Dóra Faragó

SMALL PARAQUAT RESISTANT protein controlling stress responses in higher plants
9:35-9:50 O-11
Tamás Annus

Zebrafish as a model for Bloom’s syndrome
O-16
Károly Fátyol
Involvement of RNA binding proteins in plant antiviral responses
9:50-10:05 O-12
Viktor Vedelek
Changes of mitochondria in Drosophila melanogaster spermatids
O-17
László Kozma-Bognár
Ubiquitin protease 12 affects the function of the circadian clock in Arabidopsis thaliana
10:05-10:20 O-13
Szilárd Szikora
Nanoscale reconstruction of flight muscle sarcomeres
O-18
Nikoletta Murvai
The protective effect of ERD14 – the versatility of an intrinsically disordered chaperon
10:20-11:00 Coffee break
11:00-12:50 Epienetics & Regulation of Gene expression / Congress Hall
Chair: Imre Boros
Protein structure & function / Session Room Liget I.
Chair: László Nyitray
11:00-11:20 O-19
Zoltán Ivics
Transposase and host factor determinants of target site selection by DNA transposons
O-26
László Nyitray
Two tales of protein tails: regulation by S100 protein binding and phosphorylation
11:20-11:35 O-20
Ferenc Jankovics
Small ovary (sov): a novel heterochromatin regulator in Drosophila
O-27
András Benedek
Insights into the structural background of dUTPase inhibition by a proteinaceous inhibitor
11:35-11:50 O-21
Lóránt Székvölgyi
R-loop binding proteins: from chromatin to therapeutic targeting
O-28
Ágnes Tantos
Disordered regions of Mixed Lineage Leukemia 4 (MLL4) protein are capable of RNA binding
11:50-12:05 O-22
László Imre
Regulation via PTMs, histone variants and extrachromosomal interactions are all mediated by large changes of nucleosome stability
O-29
Katalin Goda
Studying the catalytic cycle of Pgp and ABCG2 transporters
12:05-12:20 O-23
Zoltán Villányi
Ccr4-Not complex is at the core of the gene expression circuitry
O-30
Zoltán Lipinszki
Characterization of a cis-acting protein stabilization motif that functions as a universal STABILON in higher Eukaryotes
12:20-12:35 O-24
Izabella Bajusz
Germ cells unleashed: Role of Rybp in regulating germ cell determinants
O-31
Márton András Simon
Functional redundancy within the S100 protein family
12:35-12:50 O-25
Bálint L. Bálint
Chromatin level determinants of cellular identity
O-32
Jitrayut Jitonnom
Multiscale quantum modeling in biocatalysis: a tool for predicting enzymatic reactivity and selectivity
12:50-14:10 Lunch
14:10-15:20 Plenary session / Congress Hall
14:10-14:45 PL-3
Norbert Pardi
Nucleoside-modified mRNA therapeutics-developing a new class of drugs
14:45-15:20 PL-4
László Csanády
Asymmetric movements reveal distinct roles of the two ATP binding sites in the CFTR anion channel
15:20-15:30 Technical break
15:30-17:00 Genome manipulation& archeogenetics / Congress Hall
Chair: Anna Szécsényi-Nagy
Pathobiochemistry / Session Room Liget I.
Chair: Ferenc Gallyas
15:30-15:45 O-33
Tamás Fehér
Downregulating insertional mutagenesis in bacterial genomes using CRISPR-interference
O-39
Anikó Göblös
CARD14 gene variants and nuclear factor κB (NFκB) activation in pityriasis rubra pilaris
15:45-16:00 O-34
Andreea Daraba
Haploinsufficiency: mechanisms and evolution
O-40
Zsuzsanna Szvicsek
Apc mutation induces extracellular vesicle release from intestinal organoids
16:00-16:15 O-35
Péter István Kulcsár
Blackjack mutations improve the on-target activities of all increased fidelity variants of SpCas9
O-41
Marcela Buchtova
Disruption of primary cilia function initiates region-specific craniofacial defects
16:15-16:30 O-36
Bea Szeifert
Genetic investigation of archeological sites in Russia that can be associated with early Hungarians
O-42
Éva Margittai
Epigenetic role of ascorbate compartmentalization in human diseases
16:30-16:45 O-37
Endre Neparáczki
Y-chromosome haplogroups from Hun, Avar and conquering Hungarian nomadic people of the Carpathian Basin
O-43
Tibor Sághy
Loss of transglutaminase 2 sensitizes for diet-induced obesity-related inflammation, insulin resistance and hepatic steatosis
16:45-17:00 O-38
Anna Szécsényi-Nagy
Archaeogenetic evidence on the origin and social organization of the Avar period elite (7-8th centuries AD)
O-44
István Krizbai
Pattern recognition receptors and inflammasome activation in cerebral endothelial cells and pericytes
17:00-19:00 Poster discussion with coffee break – Poster session II.  (P115 – P225)
Jump to Poster session II.
20:00- Banquet

 

Day 3 – Sunday, 31 March 2019

9:30-11:00 Systems biology & Bioinformatics / Congress Hall
Chair: Zsuzsanna Dosztányi
DNA repair & Carcinogenesis / Session Room Liget I.
Chair: Lajos Haracska
9:30-9:45 O-45
Attila Csikász-Nagy
Cell cycle arrest due to proteostasis decline in aging yeast cells
O-51
Éva Bálint
A new modulator of the synthetic activity of Polymerase η
9:45-10:00 O-46
Erik Czipa
ChIPSummitDB: A comprehensive database of human transcription factor binding sites and the topological arrangements of transcription factor complexes on the DNA
O-52
Péter Burkovics
Saccharomyces cerevisiae Mgs1 protein contributes to G-quadruplex replication
10:00-10:15 O-47
Borbála Hajdú-Soltész
Identifying driver regions in hypermutated cancer genomes
O-53
Hajnalka Pálinkás
Capturing the transient profile of uracil accumulation in human genomic DNA by super-resolution microscopy and genome-wide uracil-DNA sequencing analysis
10:15-10:30 O-48
Lajos Kalmár
Linking the resistome to the microbiome in complex microbial communities
O-54
László Hiripi
Gene targeting of dUTPase in mice leads to early embryonic lethality
10:30-10:45 O-49
Balázs Ligeti
Fast and sensitive detection of pathogens from high throughput sequencing data
O-55
Gábor Harami
Molecular mechanism of legitimate DNA homology sensing by RecQ helicase
10:45-11:00 O-50
Georgina Csizmadia
Defining transmembrane regions using cryo-EM maps: the MemBlob database and server
O-56
Bernadett Szikriszt
Analysis of the mutagenic effect of platinum-based chemoterapeutic agents in cell line based model system
11:00-11:30 Coffee break
11:30-12:35 Proteomics / Congress Hall
Chair: Katalin Medzihradszky
Autophagy and intracellular trafficking  / Session Room Liget I.
Chair: Tibor Vellai
11:30-11:50 O-57
Katalin Medzihradszky
A neglected post-translational modification: extracellular O-glycosylation
O-62
Attila Boda
The role of the small GTPases Arl8 and Rab7 in crinophagic degradation
11:50-12:05 O-58
Éva Csősz
Complex proteomics and metabolomics examination of wound healing markers in glaucoma patients following trabeculectomy
O-63
Zsófia Budai
Macrophages engulf apoptotic and primary necrotic thymocytes through similar phosphatidylserine-dependent mechanisms
12:05-12:15 O-59
Gábor Juhász
Proteomics and genomics studies on pathological and physiological functioning of the nervous system
O-64
Zsolt Lakatos
Drosophila Sec20 regulates autophagy and endocytosis independently of the Golgi-to-ER retrograde transport
12:15-12:25 O-60
Simon Sugár
Analysis of the N-glycosylation of the HeLa cell lysate
O-65
Tibor Kovács
Hemocytes regulate selective autophagy during regeneration of germline stem cells in Drosophila
12:25-12:35 O-61
Zoltán Szabó
Quantitative proteomics at peak: evaluation of novel approaches in mass spectrometry based proteomics
O-66
Gábor Glatz
SNARE protein Ykt6 as swiss army knife in vesicular fusion events
12:40-13:00 Closing and award ceremony / Congress Hall
13:00- Lunch

 

Poster Session I. (P001 – P114) – Friday, 29 March 2019

P-001 Krisztina H.-Minkó
Ablation of cranial neural crest affects development of the thymus
Cell differentiation and signaling
P-002 Kinga Lénárt
Beige cells of tissue transglutaminase knock-out mice possess attenuated response to adrenergic agonists
Cell differentiation and signaling
P-003 Csaba Matta
Circadian rhythms during early chondrogenesis
Cell differentiation and signaling
P-004 Enikő Sutus
Connecting RYBP to the retinoic acid signalling pathway during neural differentiation
Cell differentiation and signaling
P-005 Abhirup Shaw
Distinct gene expression patterns, unrelated to thermogenesis, are induced in human adipocytes from the neck in response to Irisin and BMP7
Cell differentiation and signaling
P-006 Péter Kaltenecker
Examining the role of Wnt/PCP proteins in axon growth and neuronal cytoskeleton regulation
Cell differentiation and signaling
P-007 Vikas Patel
Gene expression signature of BRAF inhibitor resistant melanoma shperoids
Cell differentiation and signaling
P-008 Gergely István Varga
Headcase is a regulator of hemocyte differentiation in Drosophila melanogaster
Cell differentiation and signaling
P-009 Erika Gábor
Individual immunity of a social insect the honey bee (Apis mellifera)
Cell differentiation and signaling
P-010 Sándor Katz
Inflammatory cytokines transdifferentiate mesenteric mesothelial cells into macrophages
Cell differentiation and signaling
P-011 Balázs Barátki
Inflammatory signal-induced IL-10 production of marginal zone B cells depends on CREB
Cell differentiation and signaling
P-012 Viktória Zsiros
Internalization of GM-CSFR β is essential to initiate mesothelial-to-macrophage transition
Cell differentiation and signaling
P-013 Roland Ádám Takács
Investigating the role of septins in chondrogenic high density cultures
Cell differentiation and signaling
P-014 Éva Katona
Investigation of molecular clock elements in WM35 melanoma cells
Cell differentiation and signaling
P-015 Randa Naffa
p38 MAP kinase mediates degradation of the putative metastasis suppressor PMCA4b in BRAF mutant melanoma cells
Cell differentiation and signaling
P-016 Zoltán Márton Köhler
Proteoglycan-mediated glucose uptake and mitochondrial respiration in skeletal muscle cells
Cell differentiation and signaling
P-017 Zsófia Thalwieser
Role of protein phosphatase 2A B55α in angiogenesis
Cell differentiation and signaling
P-018 Anita Boratkó
Role of TIMAP-PP1c complex in neuronal cell differentiation
Cell differentiation and signaling
P-019 Viktória Szabó
RYBP is essential for the maturation of cardiomyocytes in vitro
Cell differentiation and signaling
P-020 György Török
Specific detection of the cell polarity regulator LKB1
Cell differentiation and signaling
P-021 Krisztina Tóth
The effect of the formin DAAM on cytoskeleton rearrangements in Drosophila melanogaster
Cell differentiation and signaling
P-022 Csaba Matta
The effects of a hyperosmotic environment on cartilage formation
Cell differentiation and signaling
P-023 Zita Lerner
The formation of Multinucleated Giant Hemocytes, the effectors of cell-mediated immune response in Drosophila ananassae
Cell differentiation and signaling
P-024 Bálint Szeder
The loss of scaffold protein Tks4 induces EMT like changes in HCT116 human colorectal carcinoma cells
Cell differentiation and signaling
P-025 Zsófia Budai
The potential role of transglutaminase 2 in skeletal muscle regeneration
Cell differentiation and signaling
P-026 Alexandra Brigitta Szarka-Kovács
The role of Mesr4 in germline stem cell differentiation
Cell differentiation and signaling
P-027 Kitti Szabó
The role of syndecan-4/Rac1 signalling in myoblast differentiation and fusion
Cell differentiation and signaling
P-028 Elham Alzyoud
Basal body composition during spermatogenesis of Drosophila melanogaster
Developmental genetics
P-029 Gabriella Gazsó-Gerhát
Examination of the redundancy between DAAM and FRL formins during pigment cell development in the Drosophila eye
Developmental genetics
P-030 Melinda Bence
Role of Su(var)2-10 gene in germ cell development of Drosophila melanogaster
Developmental genetics
P-031 Ibrahim Karam
Small ovary (sov) regulates transposon silencing by prompting heterochromatin formation in Drosophila
Developmental genetics
P-032 Péter Borkúti
Testing the biological significance of the nuclear localization of actin
Developmental genetics
P-033 Kinga Szilasi
Testis specific proteasome subunits in Drosophila melanogaster
Developmental genetics
P-034 László Henn
The role of linker Histone H1 variant in early Drosophila embryogenesis
Developmental genetics
P-035 Máté Varga
Uracil in the DNA during the early development of zebrafish
Developmental genetics
P-036 Endre Sebestyén
Chromatin fractionation sequencing for the detection of early heterochromatin alterations in Hutchinson-Gilford progeria syndrome
Epigenetics and Regulation of Gene expression
P-037 Rosevalentine Bosire
Constrained and extranucleosomal superhelicity impose a barrier to intercalation in native chromatin
Epigenetics and Regulation of Gene expression
P-038 Ranti Dev Shukla
Developing novel gene integration and amplification techniques for enhanced transgene expression in Escherichia coli
Epigenetics and Regulation of Gene expression
P-039 Eszter Gecse
Early and long term behavioral and molecular patterns evoked by toxic stresses in Caenorhabditis elegans
Epigenetics and Regulation of Gene expression
P-040 Erfaneh Firouzi Niaki
Effect of DNA targeting drugs on DNA topology
Epigenetics and Regulation of Gene expression
P-041 Judit Vágó
Epigenetic regulation of chondrogenesis in chicken micromass cell cultures
Epigenetics and Regulation of Gene expression
P-042 Gerda Wachtl
Functional studies of the domesticated human PGBD1 transposon
Epigenetics and Regulation of Gene expression
P-043 Csaba Fillér
Investigation of meiotic DNA Double-Strand Break (DSB) proteins with chromosome conformation capture techniques
Epigenetics and Regulation of Gene expression
P-044 Ildikó Kristó
Investigation the role in mRNA export of the actin binding protein, moesin
Epigenetics and Regulation of Gene expression
P-045 Zsolt Czimmerer
Prior IL-4 exposure induces chromatin remodeling and the rearrangement of LPS-activated p65 cistrome, leading to synergistic transcriptional activation of a specific gene set in macrophages
Epigenetics and Regulation of Gene expression
P-046 Zsolt Czimmerer
STAT6-mediated direct repression of inflammatory enhancers limits inflammasome activation in alternatively polarized macrophages
Epigenetics and Regulation of Gene expression
P-047 Krisztina Szabó
The effect of the CaPpz1 protein phosphatase on gene expression in Candida albicans under oxidative stress conditions
Epigenetics and Regulation of Gene expression
P-048 Brigitta M. Kállai
An improved system for in vitro analysis of protein ubiquitination
Others
P-049 Zsuzsa Bartos
Cellular trafficking of ABCG2 variants assessed by a novel dynamic approach
Others
P-050 Dilek Tekdal
Characterization of Trehalose-6-phosphate synthase and Na+/H+ antiporter genes in Turkish endemic plant species V. turcica
Others
P-051 Abu Imran Baba
CRK5 protein kinase exhibits an essential role in embryogenesis of Arabidopsis thaliana
Others
P-052 Boglárka Aszódi
Determining the optimal cell conservation method with highest proportion of cells alive after culture re-initiation
Others
P-053 Ágota Nagy
Discreet charm of the smallest APC/C subunit in Drosophila
Others
P-054 Katharina Preißinger
Dissection of Plasmodium falciparum developmental stages with multiple imaging methods
Others
P-055 Mátyás Sipiczki
Double sterility barrier and its breakdown in reproductively isolated yeast species
Others
P-056 Antal Nyeste
Establishment of an MRP4 (ABCC4) knock-out cell line using CRISPR/Cas9 system
Others
P-057 Bálint Biró
Expression patterns of motilin, gastrin, ghrelin and somatostatin in association with the Left Displaced Abomasum in cattle
Others
P-058 Orsolya Palócz
Frequency of a single nucleotide substitution of ABCB1 gene in herding dog breeds in Hungary
Others
P-059 Katalin Vincze
Genetic risk variants in the major histocompatibility complex region in a Hungarian schizophrenia sample
Others
P-060 Dilek Tekdal
High-throughput targeted microsatellite marker development in Vuralia turcica (Piyan)
Others
P-061 Anett Vranesics
In vivo diffusion tensor imaging of the brains of stressed rats
Others
P-062 Syed Muhammad Nurulain
Investigation of cholinergic enzymes in heroin and polydrug addiction
Others
P-063 Tibor Hajdú
Isolation and culturing of human cutaneous melanocytes
Others
P-064 Balázs Libisch
Metagenomic analysis of acquired antibiotic resistance genes in the gut microbiome of wild boars (Sus scrofa)
Others
P-065 Krisztina Jámbor
Ostepontin splice variants expression in malignant melanoma cell lines
Others
P-066 Dóra Faragó
PlantSize: an affordable non-destructive method to measure plant size and color in vitro
Others
P-067 Gábor Rigó
Role of the Arabidopsis thaliana CRK5 protein kinase in the gravitropic response
Others
P-068 Krisztina Percze
Selection of aptamers of therapeutic potential for respiratory syncytial virus infection
Others
P-069 András Tálas
Sequence specificity of Cas9 variants on one million target sequences
Others
P-070 Norbert Andrási
The Heat Shock Factor A4A regulates responses to combined salt and heat stresses
Others
P-071 Laura Zsigmond
The role of Arabidopsis thaliana mitochondrial proteins in stress responses
Others
P-072 Péter Gudmann
Triacylglycerol-deficient mutants exhibit altered surface membrane properties in fission yeast
Others
P-073 Ágota Nagy
Ubiquitin pool dynamics revealed by quantifying ubiquitin forms in Drosophila UPS mutants
Others
P-074 Anna Müller
A new approach to the experimental analysis of the human transmembrane proteome
Protein structure and function
P-075 Nikolett Zsibrita
A simple E. coli system for studying sequence-specific DNA binding of proteins
Protein structure and function
P-076 Andrea Teréz Vig
Activities of Flightless-I (Fli-I) in the organisation of actin cytoskeleton
Protein structure and function
P-077 Anikó Mentes, Erzsébet Fichó
Analysis of Heterodimeric “Mutual Synergistic Folding”-complexes
Protein structure and function
P-078 Nikolett Király
Annexin A2 is a new interacting partner of TIMAP in endothelial cells
Protein structure and function
P-079 Ahmed Rozza
Atomistic modelling of gas molecule diffusion in H-NOX proteins
Protein structure and function
P-080 István Földi
Characterization of the direct and indirect interactions between formins and microtubules
Protein structure and function
P-081 Annamária Kiss-Tóth
Comprehensive analysis of intrinsically disordered regions in postsynaptic scaffold proteins
Protein structure and function
P-082 Zsuzsánna Nagy
Developing a novel protein-tagging, immunodetection and purification system
Protein structure and function
P-083 Áthelyezve a P-II szekció végére / Moved to the end of session P-II
P-084 Zsuzsanna Gyöngy
Elucidation of the conformational changes of ABCG2 in permeabilized cells
Protein structure and function
P-085 Bence Kiss
Examination of BFSP1 (Beaded Filament structural Protein 1 or Filensin) tumor specific splice variants in ex vivo human tumorous tissue and human serum samples
Protein structure and function
P-086 Zsuzsa Szabó
In vitro characterisation of human transglutaminase 4 activity and biological stability
Protein structure and function
P-087 Tamás Horváth
Intrinsically disordered linkers impart processivity on enzymes by spatial confinement of binding domains
Protein structure and function
P-088 Tamás Madarász
Investigating the regulatory function of IBAR and IRSp53 proteins in the formation of membrane nanotubes
Protein structure and function
P-089 Rita Pancsa
Mislocalized phase separation by oncogenic fusion proteins: a frequent cause of cancers
Protein structure and function
P-090 Julianna Oláh
Multiscale modelling of protein-ligand interactions in heme enzymes
Protein structure and function
P-091 Hasan Mamar
Mutational analysis of a deubiquitylating enzyme-coding gene in Drosophila melanogaster
Protein structure and function
P-092 Angéla Békési
Nanobodies as potent tools in structural and functional studies of large multidomain partially disordered proteins
Protein structure and function
P-093 Éva Schád
Relationship between interfaces, binding strength and specificity of disordered protein complexes
Protein structure and function
P-094 Wijitra Meelua
Revealing the catalytic mechanism and stereoselectivity of the dinuclear zinc enzyme dihydropyrimidinase with quantum chemical approach
Protein structure and function
P-095 Eszter Nagy-Kanta, Zita Harmat
Structural and functional characterization of the GKAP post-synaptic density scaffold protein
Protein structure and function
P-096 Marcell Váradi
Structural determinants of the long-distance interaction between human UPF1 and UPF2
Protein structure and function
P-097 Péter Ecsédi
Structural determination of p53 – S100A4 complex using annexin A2 as a novel crystallization chaperone
Protein structure and function
P-098 Péter Gaszler
Structural differences between Gelsolin and Flightless-I proteins and their behaviour in the presence and absence of Ca2+-ion
Protein structure and function
P-099 Beáta Szabó
The effect of phosphorylation on the RNA-binding capacity of the Ezh2 disordered loop region
Protein structure and function
P-100 Alexandra Holló
The effect of the MYO16 ankyrin domain on the actomyosin system
Protein structure and function
P-101 Adrienn Skopál
The role of adenosine 2A receptor activation in the vesicular trafficking of macrophages
Protein structure and function
P-102 Rawan Abukhairan
The role of polyQ region in the RNA binding of Mixed Lineage Leukemia 4 (MLL4) protein
Protein structure and function
P-103 Julia K. Varga
Using ubiquitinated positions to gather membrane protein topology data
Protein structure and function
P-104 Dávid Kis
Acute and chronic health effects of extracellular vesicles from irradiated mice
Stem cells
P-105 Edit Hathy
CRISPR genome editing based isogenic induced pluripotent stem cell system for schizophrenia disease modeling
Stem cells
P-106 Elen Gócza
Discovery the role of MIR-302 cluster in chicken and rabbit stem cells
Stem cells
P-108 Julianna Lilienberg
Effect of microglial cells on the neurite outgrowth of human stem cell-derived neural progenitor cells
Stem cells
P-109 Dóra Reé
Establishment and characterization of DGCR8 knock-out human embryonic stem cells for modelling DiGeorge syndrome
Stem cells
P-110 Bálint Jezsó
How expression pattern of ABCG2 does change during neural differentiation?
Stem cells
P-111 Viktória Halasy
Role of CXCR4-CXCL12 signaling in colonization of developing bursa of Fabricius
Stem cells
P-112 Eszter Szabó
Stem cell-based modelling of cardiac and neuronal phenotypes in DiGeorge syndrome
Stem cells
P-113 Tamás Kovács
The role of BMP signaling and the embryonic ceca in the enteric nervous system development
Stem cells
P-114 Pál Botó
Zbtb46 mediated suppression of the embryonic stem cell derived myeloid lineage development
Stem cells
P-162 Mária Husvéth-Tóth
In vitro modelling the protective effect of rosuvastatin against doxorubicin-induced endothelial injury
Drug development
P-171 Ildikó Bódi
A new phenotype in the thymus of children operated with atrial septal defect
Molecular mechanism of diseases

Poster Session II. (P115 – P225) – Saturday, 30 March 2019

P-115 Lili Anna Kenéz
A new relationship between miniCORVET and HOPS tethering complexes
Autophagy and intracellular trafficking
P-116 Marianna Holczer
A systems biological analysis of AMPK-mTOR-ULK1 module-controlled autophagy
Autophagy and intracellular trafficking
P-117 Sarolta Tóth
C11.1 protein is a new regulator of actin network rearrangement involved in exocytosis of secretory granules
Autophagy and intracellular trafficking
P-118 Renáta Gáspár
Cardiomyocytes are protected by kynurenic acid against simulated ischemia/reperfusion injury
Autophagy and intracellular trafficking
P-119 Margita Márton
Connections between genes of PERK pathway upon endoplasmic reticulum stress
Autophagy and intracellular trafficking
P-120 Hussein Abuammar
Deciphering the role of the small GTPase Rab27 in Drosophila autophagy
Autophagy and intracellular trafficking
P-121 Erika Fodor
Developing genetic tools to study the role of autophagy in zebrafish development and tissue homeostasis
Autophagy and intracellular trafficking
P-122 Péter Nánási
Doxorubicin induces large-scale and distinct H2A and H2B redistribution in live cells
Autophagy and intracellular trafficking
P-123 Janka Szinyákovics
EDTP and MTMR14 lipid phosphatases promote brain aging by progressively downregulating autophagy throughout adulthood
Autophagy and intracellular trafficking
P-124 Zoltán Kovács
FRAP analysis of the nuclear import of the cytoskeletal Moesin protein
Autophagy and intracellular trafficking
P-125 Dalma Feil-Börcsök
Investigation of sorting nexin functions in Drosophila tissues
Autophagy and intracellular trafficking
P-126 Ármin Sőth
Investigation of the interaction of two endosomal tethering factors, Rabenosyn-5 and Vps18
Autophagy and intracellular trafficking
P-127 Dávid Tóth
Links between DNA repair proteins and autophagy regulation
Autophagy and intracellular trafficking
P-128 Asha Kiran Maddali
Lipids of autophagic membranes and their functional roles
Autophagy and intracellular trafficking
P-129 Zsófia Simon-Vecsei
Loss of Vps18 affect autophagy and cell adhesion of mammalian cells
Autophagy and intracellular trafficking
P-130 András Rubics
Rab3GAP-Rab18 module promotes autolysosome maturation through Atg14-PI3K complex
Autophagy and intracellular trafficking
P-131 Poulami Banik
The role of the autophagy machinery in glial engulfment of axon debris
Autophagy and intracellular trafficking
P-132 Zsófia Gyetvai
The role of the SNARE protein Ykt6 in crinophagy
Autophagy and intracellular trafficking
P-133 Kinga Tagscherer
Two myotubularin phosphatases, EDTP and Mtmr6, differentially regulate autophagy in Drosophila melanogaster
Autophagy and intracellular trafficking
P-134 Győző Szenci
Ykt6 acts as a non-canonical SNARE in autophagosome-lysosome fusion
Autophagy and intracellular trafficking
P-135 Péter Szikora
Analyzing the effect of splicing factor mutations with information theoretic methods
Bioinformatics
P-136 Ádám Nagy
Analyzing the prognostic value of immunomodulatory genes in multiple types of solid tumors
Bioinformatics
P-137 Torda Varga
COMPARE1K+, a bioinformatic pipeline and an R package to analyse the evolution of thousands of genomes
Bioinformatics
P-138 Ilona Tornyi
Comprehensive analysis of signal peptide prediction algorithms
Bioinformatics
P-139 Emese Tolnai
Effect of dietary fructooligosacharide (FOS), carotenoids, anthocyanins and probiotics supplementation on the intestinal microbiome in broiler chickens
Bioinformatics
P-140 Noam Makmal
Epigenetic determinants of gene expression noise in hematopoietic stem cells
Bioinformatics
P-141 Áron Bartha
Features of exceptional survivors – defining advanced stage cancer patients with prolonged overall survival
Bioinformatics
P-142 Gábor Fidler
Impact of different alterations of sample preparation, lysis protocols and DNA separation on shifts in composition of broiler chicken microbiota
Bioinformatics
P-143 Menyhart Otília
Potential new therapeutic targets in colorectal carcinoma linked to driver mutations
Bioinformatics
P-144 Zoltán Gáspári
Prediction of single α-helices in large sequence sets
Bioinformatics
P-145 Mónika Mórocz
An old player in a new role: HLTF tumour suppressor fighting shoulder to shoulder with FANCJ against replication stress
DNA repair and Carcinogenesis
P-146 Karola Almási
Analyses of the function of Saccharomyces cerevisiae Mgs1 protein in G-quadruplex replication
DNA repair and Carcinogenesis
P-147 Ádám Póti
Correlation of homologous recombination deficiency induced mutational signatures with sensitivity to PARP inhibitors and cytotoxic agents
DNA repair and Carcinogenesis
P-148 Enikő Sajben-Nagy
Development of new reporter systems to monitor the accuracy of G4 replication in Saccharomyces cerevisiae
DNA repair and Carcinogenesis
P-149 Sham Jdeed
Dissecting molecular pathways to understand breast cancer chemoprevention
DNA repair and Carcinogenesis
P-150 András Penyige
Identification of differentially-expressed miRNAs in plasma samples of ovarian cancer patients
DNA repair and Carcinogenesis
P-151 Rita Hirmondó
Investigation of the mutator effects of various genotoxic stresses provides insight into the mechanism of drug resistance development in Mycobacteria
DNA repair and Carcinogenesis
P-152 Szabó Judit Eszter
Investigation of uracil-DNA repair in Staphylococcus aureus
DNA repair and Carcinogenesis
P-153 Szilvia Juhász
PARylation and DNA accessibility during the DNA damage response
DNA repair and Carcinogenesis
P-154 Kata Dudás
Regulatory function of ZBTB1 in the DNA damage tolerance pathways
DNA repair and Carcinogenesis
P-155 Kovács Mihály
Single-molecule techniques reveal how proteins can access DNA coated by SSB proteins
DNA repair and Carcinogenesis
P-156 Dániel Molnár
The effects of genotoxic stress factors on DNA repair system in Mycobacteria
DNA repair and Carcinogenesis
P-157 Virág Székely
A novel fluorescence-based assay to characterize transporters involved in hepatic detoxification
Drug development
P-158 Orsolya Lang
Design of novel heterocyclic molecules for apoptosis induction
Drug development
P-159 Mohana Krishna Gopisetty
Endoplasmic reticulum stress: major player in size-dependent inhibition of P-glycoprotein by silver nanoparticles in multidrug-resistant breast cancer cells
Drug development
P-160 Virág Demján
Impact of Stellaria media tea lyophilizate on hypercholesterolemia in rats
Drug development
P-161 László Kőhidai
Impedance-based analysis – A dedicated technique to characterize efficacy of novel antitumour compounds
Drug development
P-162 Áthelyezve a P-I szekció végére / Moved to the end of session P-I
P-163 István Szász
New perspective in melanoma treatment – Targeting endoplasmatic reticulum stress
Drug development
P-164 Réka Laczkó-Rigó
Structural dissection of 13-epiestrones based on the interaction with the steroid transporting human Organic Anion-Transporting Polypeptide, OATP2B1
Drug development
P-165 Kuljeet Singh
The effect of sour cherry flavonoids and Anthocyanins on Pgp activity
Drug development
P-166 Dániel Gerber
Advances of bioinformatic methodology in archaeogenetics
Human genetics and archaeogenetics
P-167 Gloria Zodanu
Chromosome 22q11 copy number variations in paediatric and adult patients with congenital heart defects
Human genetics and archaeogenetics
P-168 Kornélia Tripolszki
Computational and functional analyses of angiogenin mutations identified in Hungarian patients with amyotrophic lateral sclerosis
Human genetics and archaeogenetics
P-169 Kitti Maár
Maternal lineages from 10th century commoner cemeteries of the Carpathian Basin
Human genetics and archaeogenetics
P-170 Éva Viola Surányi
A comprehensive analysis of the contribution of genotoxic stress conditions to the development of antibiotic resistance genes in Mycobacteria
Molecular mechanism of diseases
P-171 Áthelyezve a P-I szekció végére / Moved to the end of session P-I
P-172 Máté Varga
A new zebrafish model for Pseudoxanthoma elasticum (PXE)
Molecular mechanism of diseases
P-173 Orsolya Mózner
ABCG2 mutations found in gout patients have various effects on the expression of the protein
Molecular mechanism of diseases
P-174 Ádám Tiszlavicz
Acquired cellular stress resistance in the absence of heat shock protein induction
Molecular mechanism of diseases
P-175 Vince Szegeczki
Alterations of PACAP signalling in testis of Alzheimer’s disease modelling mice
Molecular mechanism of diseases
P-176 Csilla Szűcs-Somogyi
Atypical in vitro chondrogenesis upon Transient Receptor Potential Vanilloid 4 modulation
Molecular mechanism of diseases
P-177 Tomasz Poplawski
Base excision repair in Rheumatoid arthritis – a correlation of DNA repair efficiency with the BER genes polymorphisms.
Molecular mechanism of diseases
P-178 Dominika Kovács
Clinically used PARP inhibitor olaparib protects against oxidative stress-induced epithelial barrier dysfunction in vitro
Molecular mechanism of diseases
P-179 Petra Diószegi
Decorin protects cardiomyocytes against doxorubicin-induced cytotoxicity
Molecular mechanism of diseases
P-180 Márton Szabó
Diet-induced hypercholesterolemia is associated with alterations in cardiac gene expression profile
Molecular mechanism of diseases
P-181 Renáta Hamar
dkc1 mutations are associated with changes in tp53 expression and growth impairment
Molecular mechanism of diseases
P-182 Ireneusz Majsterek
Evaluation of BDNF and HSP70 gene expression in the pathogenesis of multiple sclerosis patient in Polish population
Molecular mechanism of diseases
P-183 Fanni Dóra
Gene expressional changes in the dorsomedial prefrontal cortex of suicide victims – an RNA sequencing study
Molecular mechanism of diseases
P-184 Kitti Andreidesz
Investigating the effects of a PARP inhibitor, HO-3089, on signaling pathways in monocrotaline-induced pulmonary hypertension in rat lung tissue
Molecular mechanism of diseases
P-185 Nikoletta Gálik
Investigation of the activation of certain DNA repair enzymes in Mycobacterium smegmatis under stress conditions
Molecular mechanism of diseases
P-186 János Schmidt
Lysophosphatidylcholine depletion in head and neck squamous cell carcinoma identifies MAGL and LYPLA1 as potential biomarkers
Molecular mechanism of diseases
P-187 Orsolya Biró
Maternal and fetal folate metabolism gene polymorphisms as risk factors for congenital heart disease
Molecular mechanism of diseases
P-188 Zsolt Matula
Mitochondrial exchange between myeloma cells and bone marrow stromal cells
Molecular mechanism of diseases
P-189 Gyöngyvér Orsolya Sándor
Pancreatic cancer patient-derived 3D organoids to analyze extracellular vesicles
Molecular mechanism of diseases
P-190 Sára Sándor
The role of endogenous retroelements in neural aging in the canine model of human senescence
Molecular mechanism of diseases
P-191 Ádám Sipos
The role of HCN2 in the development of ileus
Molecular mechanism of diseases
P-192 Gábor Hajdú
Toxic stress-specific molecular cytoprotective responses determine behavioural adaptation in C. elegans
Molecular mechanism of diseases
P-193 Ádám Pap
A neglected post-translational modification: extracellular O-glycosylation
Proteomics
P-194 Róbert Király
An attempt to identify interacting partners and substrates of transglutaminase 4
Proteomics
P-195 Ervin Gyenge
Analysis of salivary protein profiles in oral leukoplakia, oral lichen planus and oral squamous cell carcinoma using proteomics techniques
Proteomics
P-196 Katalin Kékesi
Chronic cerebral hypoperfusion induced synaptic proteomic changes in rat central nervous system
Proteomics
P-197 Éva Csősz
Dissecting the uteroptrophic effect of estradiol in rodents by mass spectrometry-based proteomics
Proteomics
P-198 Márton Gyula Milley
Effect of repeated measurements and choice of database search engines in bottom-up proteomics
Proteomics
P-199 Balázs Vedelek
Identification and validation of H1 interacting partners
Proteomics
P-200 Bálint Péterfia
Interaction of the postsynaptic scaffold proteins GKAP and Shank-1
Proteomics
P-201 Bella Bruszel
Investigation of serum protein biomarkers for human glioblastoma multiforme
Proteomics
P-202 Gábor Kecskeméti
Investigation of the effect of overexpression of different ABC transporters on the cell membrane proteome
Proteomics
P-203 Gábor Tóth
On-tissue digestion of prostate cancer biopsies for proteomics
Proteomics
P-204 Katalin Medzihradszky
Phosphorylation-dependent diversification of RETINOBLASTOMA RELATED protein complexes in Arabidopsis thaliana
Proteomics
P-206 Gergő Kalló
Quantitative analysis of tear proteins from patients with diabetic retinopathy with different mass spectrometry-based methods
Proteomics
P-207 Gitta Schlosser
Statistical investigation of citrulline effect on a citrullinome database
Proteomics
P-208 József Kardos
Synaptic functional disturbances leading to C1Q deposition in health and disease
Proteomics
P-209 Emese Tolnai
Alterations of certain microRNA expressions in fevered neutropenia patients
Regulatory RNAs
P-210 Beáta Boros-Oláh
Examination of R-loops and chromatin loops with chromatin conformation capture techniques
Regulatory RNAs
P-211 Éva Hamar
Identification of RNA interference-related genes in barley (Hordeum vulgare L.)
Regulatory RNAs
P-212 Anna Farkas
The role of lncRNAs and histone methyltransferases in epithelial-mesenchymal transition
Regulatory RNAs
P-213 Ábel Fóthi
Tissue-specific promoter usage regulates primary microRNA processing efficiency of the human Chromosome 19 MicroRNA Cluster
Regulatory RNAs
P-214 Anita Kurilla
Translation termination factor is regulated by readthrough and NMD through 3’UTR intron in N. crassa
Regulatory RNAs
P-215 András Kis
Utilization of CRISPR/Cas9 system for investigation of a potential new wheat miRNA targeting RNA polymerase V (Pol V) subunit
Regulatory RNAs
P-216 Emese Demián
Viral diagnostics of rootstock plantations and the complex pathogen elimination methods of grapevine by small RNA NGS
Regulatory RNAs
P-217 Dániel Baráth
Virome of Hungarian peach plantations identified by small RNA NGS
Regulatory RNAs
P-218 Bíborka Pillér
Cellular interactions in yeast colonies
Systems biology
P-219 Ildikó Karcagi
Generation of successive random deletions in E. coli reveals the evolutionary gains and limits of genome reduction
Systems biology
P-220 János Juhász
In-silico modelling of yeast colony growth
Systems biology
P-221 Bence Keömley-Horváth
Integrating molecular databases in a proteome-wide simulation environment
Systems biology
P-222 Nóra Molnár, Emese Nagy
Morphological characteristics of yeast colonies
Systems biology
P-223 Bertalan Kovács
Structural ensembles of PDZ tandem generated by externally restrained MD simulation
Systems biology
P-224 Walliyulahi Ajibola
The effect of local rifampicin treatment on the composition and resistance of the intestinal microbiota: the first steps taken
Systems biology
P-225 Eszter Németh
The genomic imprint of cancer therapies helps timing the formation of metastases
Systems biology
P-083 Rita Szilvia Kiss
Effect of protein aggregation on protein complex assemblies
Protein structure and function