Scientific Programme

Day 1 – Friday, 29 March 2019

14:00-14:10 Opening
14:10-15:20 Plenary session / Congress Hall
14:1014:45 PL-1
Lajos Haracska
Engines of carcinogenesis; what determines the speed of mutagenesis?
14:4515:20 PL-2
Péter Lénárt
Unexpected functions of the actin cytoskeleton in meiotic divisions of oocytes
15:20-16:10 Tankó awards
László Vigh
From thermosensor membranes to membrane lipid therapy
15:4516:10 TA-2
Ferenc Erdődi
Forty years with protein phosphatases: past, present and future
16:10-16:50 Coffee break
16:50-17:55 Cell differentiation & Signaling / Congress Hall
Chair: László Buday
Stem cells / Session Room Liget I.
Chair: András Nagy
16:5017:10 O-01
Gábor Bánhegyi
Ca2+ mobilization dependent reduction of the ER lumen is due to influx of cytosolic glutathione
András Nagy
Treating disease with organoids requires solutions for two major hurdles
17:10-17:25 O-02
Zoltán Kármán
Identification of novel substrates of the evolutionarily conserved PP4 phosphatase to better understand its role in mitosis
Nándor Nagy
Talpid3 regulates multiple aspects of neuromuscular patterning during gastrointestinal development in animal models and human
17:25-17:40 O-03
Gergő Kovács
Role of RYBP in balancing between early and late neural processes
Ádám Oszwald
Extracellular vesicles transmit epithelial growth factor activity in the intestinal epithelial stem cell niche
17:4017:55 O-04
Endre Kristóf
Functional characterization and gene expression patterns of human adipocytes from the neck support high thermogenic potential in the deep region
Annamária Nemes
Generating new human vascular smooth muscle cells from pluripotent stem cells
17:55-18:00 Technical break
18:00-18:45 Sponsored talks (companies) / Congress Hall
18:00-18:15 ST-1
ROCHE, Ádám Józsa
Roche Molecular Solutions in life science
18:15-18:30 ST-2
ZEISS, Gert Sonntag
Fast and Gentle 3D Superresolution
18:30-18:45 ST-3
ThermoFisher Scientific, Salvatore Conti
Ion GeneStudio S5 systems: New tools for further NGS pipelines by ThermoFisher Scientific
19:00-20:30 Welcome dinner
20:30-22:00 Poster discussion with drinks – Poster session I. (P001 – P114)
Jump to Poster session I.


Day 2 – Saturday, 30 March 2019

9:00-10:20 Developmental Genetics / Congress Hall
Chair: Rita Sinka
Plant biology / Session Room Liget I.
Chair: László Szabados
9:00-9:20 O-09
Alexander W. Bruce
Deciphering the nodal role of p38 family of mitogen-activated protein kinases (MAPKs) towards specifying primitive endoderm (PrE) fate in the inner cell mass (ICM) of late-blastocyst stage mouse pre-implantation embryo
László Szabados
Light control of salt-induced proline accumulation is mediated by ELONGATED HYPOCOTYL 5 in Arabidopsis
9:20-9:35 O-10
Viktor Honti

Analysis of sessile tissue integrity and function in Drosophila melanogaster
Dóra Faragó

SMALL PARAQUAT RESISTANT protein controlling stress responses in higher plants
9:35-9:50 O-11
Tamás Annus

Zebrafish as a model for Bloom’s syndrome
Károly Fátyol
Involvement of RNA binding proteins in plant antiviral responses
9:50-10:05 O-12
Viktor Vedelek
Changes of mitochondria in Drosophila melanogaster spermatids
László Kozma-Bognár
Ubiquitin protease 12 affects the function of the circadian clock in Arabidopsis thaliana
10:05-10:20 O-13
Szilárd Szikora
Nanoscale reconstruction of flight muscle sarcomeres
Nikoletta Murvai
The protective effect of ERD14 – the versatility of an intrinsically disordered chaperon
10:20-11:00 Coffee break
11:00-12:50 Epienetics & Regulation of Gene expression / Congress Hall
Chair: Imre Boros
Protein structure & function / Session Room Liget I.
Chair: László Nyitray
11:00-11:20 O-19
Zoltán Ivics
Transposase and host factor determinants of target site selection by DNA transposons
László Nyitray
Two tales of protein tails: regulation by S100 protein binding and phosphorylation
11:20-11:35 O-20
Ferenc Jankovics
Small ovary (sov): a novel heterochromatin regulator in Drosophila
András Benedek
Insights into the structural background of dUTPase inhibition by a proteinaceous inhibitor
11:35-11:50 O-21
Lóránt Székvölgyi
R-loop binding proteins: from chromatin to therapeutic targeting
Ágnes Tantos
Disordered regions of Mixed Lineage Leukemia 4 (MLL4) protein are capable of RNA binding
11:50-12:05 O-22
László Imre
Regulation via PTMs, histone variants and extrachromosomal interactions are all mediated by large changes of nucleosome stability
Katalin Goda
Studying the catalytic cycle of Pgp and ABCG2 transporters
12:05-12:20 O-23
Zoltán Villányi
Ccr4-Not complex is at the core of the gene expression circuitry
Zoltán Lipinszki
Characterization of a cis-acting protein stabilization motif that functions as a universal STABILON in higher Eukaryotes
12:20-12:35 O-24
Izabella Bajusz
Germ cells unleashed: Role of Rybp in regulating germ cell determinants
Márton András Simon
Functional redundancy within the S100 protein family
12:35-12:50 O-25
Bálint L. Bálint
Chromatin level determinants of cellular identity
Jitrayut Jitonnom
Multiscale quantum modeling in biocatalysis: a tool for predicting enzymatic reactivity and selectivity
12:50-14:10 Lunch
14:10-15:20 Plenary session / Congress Hall
14:10-14:45 PL-3
Norbert Pardi
Nucleoside-modified mRNA therapeutics-developing a new class of drugs
14:45-15:20 PL-4
László Csanády
Asymmetric movements reveal distinct roles of the two ATP binding sites in the CFTR anion channel
15:20-15:30 Technical break
15:30-17:00 Genome manipulation& archeogenetics / Congress Hall
Chair: Anna Szécsényi-Nagy
Pathobiochemistry / Session Room Liget I.
Chair: Ferenc Gallyas
15:30-15:45 O-33
Tamás Fehér
Downregulating insertional mutagenesis in bacterial genomes using CRISPR-interference
Anikó Göblös
CARD14 gene variants and nuclear factor κB (NFκB) activation in pityriasis rubra pilaris
15:45-16:00 O-34
Andreea Daraba
Haploinsufficiency: mechanisms and evolution
Zsuzsanna Szvicsek
Apc mutation induces extracellular vesicle release from intestinal organoids
16:00-16:15 O-35
Péter István Kulcsár
Blackjack mutations improve the on-target activities of all increased fidelity variants of SpCas9
Marcela Buchtova
Disruption of primary cilia function initiates region-specific craniofacial defects
16:15-16:30 O-36
Bea Szeifert
Genetic investigation of archeological sites in Russia that can be associated with early Hungarians
Éva Margittai
Epigenetic role of ascorbate compartmentalization in human diseases
16:30-16:45 O-37
Endre Neparáczki
Y-chromosome haplogroups from Hun, Avar and conquering Hungarian nomadic people of the Carpathian Basin
Tibor Sághy
Loss of transglutaminase 2 sensitizes for diet-induced obesity-related inflammation, insulin resistance and hepatic steatosis
16:45-17:00 O-38
Anna Szécsényi-Nagy
Archaeogenetic evidence on the origin and social organization of the Avar period elite (7-8th centuries AD)
István Krizbai
Pattern recognition receptors and inflammasome activation in cerebral endothelial cells and pericytes
17:00-19:00 Poster discussion with coffee break – Poster session II.  (P115 – P225)
Jump to Poster session II.
20:00- Banquet


Day 3 – Sunday, 31 March 2019

9:30-11:00 Systems biology & Bioinformatics / Congress Hall
Chair: Zsuzsanna Dosztányi
DNA repair & Carcinogenesis / Session Room Liget I.
Chair: Lajos Haracska
9:30-9:45 O-45
Attila Csikász-Nagy
Cell cycle arrest due to proteostasis decline in aging yeast cells
Éva Bálint
A new modulator of the synthetic activity of Polymerase η
9:45-10:00 O-46
Erik Czipa
ChIPSummitDB: A comprehensive database of human transcription factor binding sites and the topological arrangements of transcription factor complexes on the DNA
Péter Burkovics
Saccharomyces cerevisiae Mgs1 protein contributes to G-quadruplex replication
10:00-10:15 O-47
Borbála Hajdú-Soltész
Identifying driver regions in hypermutated cancer genomes
Hajnalka Pálinkás
Capturing the transient profile of uracil accumulation in human genomic DNA by super-resolution microscopy and genome-wide uracil-DNA sequencing analysis
10:15-10:30 O-48
Lajos Kalmár
Linking the resistome to the microbiome in complex microbial communities
László Hiripi
Gene targeting of dUTPase in mice leads to early embryonic lethality
10:30-10:45 O-49
Balázs Ligeti
Fast and sensitive detection of pathogens from high throughput sequencing data
Gábor Harami
Molecular mechanism of legitimate DNA homology sensing by RecQ helicase
10:45-11:00 O-50
Georgina Csizmadia
Defining transmembrane regions using cryo-EM maps: the MemBlob database and server
Bernadett Szikriszt
Analysis of the mutagenic effect of platinum-based chemoterapeutic agents in cell line based model system
11:00-11:30 Coffee break
11:30-12:35 Proteomics / Congress Hall
Chair: Katalin Medzihradszky
Autophagy and intracellular trafficking  / Session Room Liget I.
Chair: Tibor Vellai
11:30-11:50 O-57
Katalin Medzihradszky
A neglected post-translational modification: extracellular O-glycosylation
Attila Boda
The role of the small GTPases Arl8 and Rab7 in crinophagic degradation
11:50-12:05 O-58
Éva Csősz
Complex proteomics and metabolomics examination of wound healing markers in glaucoma patients following trabeculectomy
Zsófia Budai
Macrophages engulf apoptotic and primary necrotic thymocytes through similar phosphatidylserine-dependent mechanisms
12:05-12:15 O-59
Gábor Juhász
Proteomics and genomics studies on pathological and physiological functioning of the nervous system
Zsolt Lakatos
Drosophila Sec20 regulates autophagy and endocytosis independently of the Golgi-to-ER retrograde transport
12:15-12:25 O-60
Simon Sugár
Analysis of the N-glycosylation of the HeLa cell lysate
Tibor Kovács
Hemocytes regulate selective autophagy during regeneration of germline stem cells in Drosophila
12:25-12:35 O-61
Zoltán Szabó
Quantitative proteomics at peak: evaluation of novel approaches in mass spectrometry based proteomics
Gábor Glatz
SNARE protein Ykt6 as swiss army knife in vesicular fusion events
12:40-13:00 Closing and award ceremony / Congress Hall
13:00- Lunch


Poster Session I. (P001 – P114) – Friday, 29 March 2019

P-001 Krisztina H.-Minkó
Ablation of cranial neural crest affects development of the thymus
Cell differentiation and signaling
P-002 Kinga Lénárt
Beige cells of tissue transglutaminase knock-out mice possess attenuated response to adrenergic agonists
Cell differentiation and signaling
P-003 Csaba Matta
Circadian rhythms during early chondrogenesis
Cell differentiation and signaling
P-004 Enikő Sutus
Connecting RYBP to the retinoic acid signalling pathway during neural differentiation
Cell differentiation and signaling
P-005 Abhirup Shaw
Distinct gene expression patterns, unrelated to thermogenesis, are induced in human adipocytes from the neck in response to Irisin and BMP7
Cell differentiation and signaling
P-006 Péter Kaltenecker
Examining the role of Wnt/PCP proteins in axon growth and neuronal cytoskeleton regulation
Cell differentiation and signaling
P-007 Vikas Patel
Gene expression signature of BRAF inhibitor resistant melanoma shperoids
Cell differentiation and signaling
P-008 Gergely István Varga
Headcase is a regulator of hemocyte differentiation in Drosophila melanogaster
Cell differentiation and signaling
P-009 Erika Gábor
Individual immunity of a social insect the honey bee (Apis mellifera)
Cell differentiation and signaling
P-010 Sándor Katz
Inflammatory cytokines transdifferentiate mesenteric mesothelial cells into macrophages
Cell differentiation and signaling
P-011 Balázs Barátki
Inflammatory signal-induced IL-10 production of marginal zone B cells depends on CREB
Cell differentiation and signaling
P-012 Viktória Zsiros
Internalization of GM-CSFR β is essential to initiate mesothelial-to-macrophage transition
Cell differentiation and signaling
P-013 Roland Ádám Takács
Investigating the role of septins in chondrogenic high density cultures
Cell differentiation and signaling
P-014 Éva Katona
Investigation of molecular clock elements in WM35 melanoma cells
Cell differentiation and signaling
P-015 Randa Naffa
p38 MAP kinase mediates degradation of the putative metastasis suppressor PMCA4b in BRAF mutant melanoma cells
Cell differentiation and signaling
P-016 Zoltán Márton Köhler
Proteoglycan-mediated glucose uptake and mitochondrial respiration in skeletal muscle cells
Cell differentiation and signaling
P-017 Zsófia Thalwieser
Role of protein phosphatase 2A B55α in angiogenesis
Cell differentiation and signaling
P-018 Anita Boratkó
Role of TIMAP-PP1c complex in neuronal cell differentiation
Cell differentiation and signaling
P-019 Viktória Szabó
RYBP is essential for the maturation of cardiomyocytes in vitro
Cell differentiation and signaling
P-020 György Török
Specific detection of the cell polarity regulator LKB1
Cell differentiation and signaling
P-021 Krisztina Tóth
The effect of the formin DAAM on cytoskeleton rearrangements in Drosophila melanogaster
Cell differentiation and signaling
P-022 Csaba Matta
The effects of a hyperosmotic environment on cartilage formation
Cell differentiation and signaling
P-023 Zita Lerner
The formation of Multinucleated Giant Hemocytes, the effectors of cell-mediated immune response in Drosophila ananassae
Cell differentiation and signaling
P-024 Bálint Szeder
The loss of scaffold protein Tks4 induces EMT like changes in HCT116 human colorectal carcinoma cells
Cell differentiation and signaling
P-025 Zsófia Budai
The potential role of transglutaminase 2 in skeletal muscle regeneration
Cell differentiation and signaling
P-026 Alexandra Brigitta Szarka-Kovács
The role of Mesr4 in germline stem cell differentiation
Cell differentiation and signaling
P-027 Kitti Szabó
The role of syndecan-4/Rac1 signalling in myoblast differentiation and fusion
Cell differentiation and signaling
P-028 Elham Alzyoud
Basal body composition during spermatogenesis of Drosophila melanogaster
Developmental genetics
P-029 Gabriella Gazsó-Gerhát
Examination of the redundancy between DAAM and FRL formins during pigment cell development in the Drosophila eye
Developmental genetics
P-030 Melinda Bence
Role of Su(var)2-10 gene in germ cell development of Drosophila melanogaster
Developmental genetics
P-031 Ibrahim Karam
Small ovary (sov) regulates transposon silencing by prompting heterochromatin formation in Drosophila
Developmental genetics
P-032 Péter Borkúti
Testing the biological significance of the nuclear localization of actin
Developmental genetics
P-033 Kinga Szilasi
Testis specific proteasome subunits in Drosophila melanogaster
Developmental genetics
P-034 László Henn
The role of linker Histone H1 variant in early Drosophila embryogenesis
Developmental genetics
P-035 Máté Varga
Uracil in the DNA during the early development of zebrafish
Developmental genetics
P-036 Endre Sebestyén
Chromatin fractionation sequencing for the detection of early heterochromatin alterations in Hutchinson-Gilford progeria syndrome
Epigenetics and Regulation of Gene expression
P-037 Rosevalentine Bosire
Constrained and extranucleosomal superhelicity impose a barrier to intercalation in native chromatin
Epigenetics and Regulation of Gene expression
P-038 Ranti Dev Shukla
Developing novel gene integration and amplification techniques for enhanced transgene expression in Escherichia coli
Epigenetics and Regulation of Gene expression
P-039 Eszter Gecse
Early and long term behavioral and molecular patterns evoked by toxic stresses in Caenorhabditis elegans
Epigenetics and Regulation of Gene expression
P-040 Erfaneh Firouzi Niaki
Effect of DNA targeting drugs on DNA topology
Epigenetics and Regulation of Gene expression
P-041 Judit Vágó
Epigenetic regulation of chondrogenesis in chicken micromass cell cultures
Epigenetics and Regulation of Gene expression
P-042 Gerda Wachtl
Functional studies of the domesticated human PGBD1 transposon
Epigenetics and Regulation of Gene expression
P-043 Csaba Fillér
Investigation of meiotic DNA Double-Strand Break (DSB) proteins with chromosome conformation capture techniques
Epigenetics and Regulation of Gene expression
P-044 Ildikó Kristó
Investigation the role in mRNA export of the actin binding protein, moesin
Epigenetics and Regulation of Gene expression
P-045 Zsolt Czimmerer
Prior IL-4 exposure induces chromatin remodeling and the rearrangement of LPS-activated p65 cistrome, leading to synergistic transcriptional activation of a specific gene set in macrophages
Epigenetics and Regulation of Gene expression
P-046 Zsolt Czimmerer
STAT6-mediated direct repression of inflammatory enhancers limits inflammasome activation in alternatively polarized macrophages
Epigenetics and Regulation of Gene expression
P-047 Krisztina Szabó
The effect of the CaPpz1 protein phosphatase on gene expression in Candida albicans under oxidative stress conditions
Epigenetics and Regulation of Gene expression
P-048 Brigitta M. Kállai
An improved system for in vitro analysis of protein ubiquitination
P-049 Zsuzsa Bartos
Cellular trafficking of ABCG2 variants assessed by a novel dynamic approach
P-050 Dilek Tekdal
Characterization of Trehalose-6-phosphate synthase and Na+/H+ antiporter genes in Turkish endemic plant species V. turcica
P-051 Abu Imran Baba
CRK5 protein kinase exhibits an essential role in embryogenesis of Arabidopsis thaliana
P-052 Boglárka Aszódi
Determining the optimal cell conservation method with highest proportion of cells alive after culture re-initiation
P-053 Ágota Nagy
Discreet charm of the smallest APC/C subunit in Drosophila
P-054 Katharina Preißinger
Dissection of Plasmodium falciparum developmental stages with multiple imaging methods
P-055 Mátyás Sipiczki
Double sterility barrier and its breakdown in reproductively isolated yeast species
P-056 Antal Nyeste
Establishment of an MRP4 (ABCC4) knock-out cell line using CRISPR/Cas9 system
P-057 Bálint Biró
Expression patterns of motilin, gastrin, ghrelin and somatostatin in association with the Left Displaced Abomasum in cattle
P-058 Orsolya Palócz
Frequency of a single nucleotide substitution of ABCB1 gene in herding dog breeds in Hungary
P-059 Katalin Vincze
Genetic risk variants in the major histocompatibility complex region in a Hungarian schizophrenia sample
P-060 Dilek Tekdal
High-throughput targeted microsatellite marker development in Vuralia turcica (Piyan)
P-061 Anett Vranesics
In vivo diffusion tensor imaging of the brains of stressed rats
P-062 Syed Muhammad Nurulain
Investigation of cholinergic enzymes in heroin and polydrug addiction
P-063 Tibor Hajdú
Isolation and culturing of human cutaneous melanocytes
P-064 Balázs Libisch
Metagenomic analysis of acquired antibiotic resistance genes in the gut microbiome of wild boars (Sus scrofa)
P-065 Krisztina Jámbor
Ostepontin splice variants expression in malignant melanoma cell lines
P-066 Dóra Faragó
PlantSize: an affordable non-destructive method to measure plant size and color in vitro
P-067 Gábor Rigó
Role of the Arabidopsis thaliana CRK5 protein kinase in the gravitropic response
P-068 Krisztina Percze
Selection of aptamers of therapeutic potential for respiratory syncytial virus infection
P-069 András Tálas
Sequence specificity of Cas9 variants on one million target sequences
P-070 Norbert Andrási
The Heat Shock Factor A4A regulates responses to combined salt and heat stresses
P-071 Laura Zsigmond
The role of Arabidopsis thaliana mitochondrial proteins in stress responses
P-072 Péter Gudmann
Triacylglycerol-deficient mutants exhibit altered surface membrane properties in fission yeast
P-073 Ágota Nagy
Ubiquitin pool dynamics revealed by quantifying ubiquitin forms in Drosophila UPS mutants
P-074 Anna Müller
A new approach to the experimental analysis of the human transmembrane proteome
Protein structure and function
P-075 Nikolett Zsibrita
A simple E. coli system for studying sequence-specific DNA binding of proteins
Protein structure and function
P-076 Andrea Teréz Vig
Activities of Flightless-I (Fli-I) in the organisation of actin cytoskeleton
Protein structure and function
P-077 Anikó Mentes, Erzsébet Fichó
Analysis of Heterodimeric “Mutual Synergistic Folding”-complexes
Protein structure and function
P-078 Nikolett Király
Annexin A2 is a new interacting partner of TIMAP in endothelial cells
Protein structure and function
P-079 Ahmed Rozza
Atomistic modelling of gas molecule diffusion in H-NOX proteins
Protein structure and function
P-080 István Földi
Characterization of the direct and indirect interactions between formins and microtubules
Protein structure and function
P-081 Annamária Kiss-Tóth
Comprehensive analysis of intrinsically disordered regions in postsynaptic scaffold proteins
Protein structure and function
P-082 Zsuzsánna Nagy
Developing a novel protein-tagging, immunodetection and purification system
Protein structure and function
P-083 Áthelyezve a P-II szekció végére / Moved to the end of session P-II
P-084 Zsuzsanna Gyöngy
Elucidation of the conformational changes of ABCG2 in permeabilized cells
Protein structure and function
P-085 Bence Kiss
Examination of BFSP1 (Beaded Filament structural Protein 1 or Filensin) tumor specific splice variants in ex vivo human tumorous tissue and human serum samples
Protein structure and function
P-086 Zsuzsa Szabó
In vitro characterisation of human transglutaminase 4 activity and biological stability
Protein structure and function
P-087 Tamás Horváth
Intrinsically disordered linkers impart processivity on enzymes by spatial confinement of binding domains
Protein structure and function
P-088 Tamás Madarász
Investigating the regulatory function of IBAR and IRSp53 proteins in the formation of membrane nanotubes
Protein structure and function
P-089 Rita Pancsa
Mislocalized phase separation by oncogenic fusion proteins: a frequent cause of cancers
Protein structure and function
P-090 Julianna Oláh
Multiscale modelling of protein-ligand interactions in heme enzymes
Protein structure and function
P-091 Hasan Mamar
Mutational analysis of a deubiquitylating enzyme-coding gene in Drosophila melanogaster
Protein structure and function
P-092 Angéla Békési
Nanobodies as potent tools in structural and functional studies of large multidomain partially disordered proteins
Protein structure and function
P-093 Éva Schád
Relationship between interfaces, binding strength and specificity of disordered protein complexes
Protein structure and function
P-094 Wijitra Meelua
Revealing the catalytic mechanism and stereoselectivity of the dinuclear zinc enzyme dihydropyrimidinase with quantum chemical approach
Protein structure and function
P-095 Eszter Nagy-Kanta, Zita Harmat
Structural and functional characterization of the GKAP post-synaptic density scaffold protein
Protein structure and function
P-096 Marcell Váradi
Structural determinants of the long-distance interaction between human UPF1 and UPF2
Protein structure and function
P-097 Péter Ecsédi
Structural determination of p53 – S100A4 complex using annexin A2 as a novel crystallization chaperone
Protein structure and function
P-098 Péter Gaszler
Structural differences between Gelsolin and Flightless-I proteins and their behaviour in the presence and absence of Ca2+-ion
Protein structure and function
P-099 Beáta Szabó
The effect of phosphorylation on the RNA-binding capacity of the Ezh2 disordered loop region
Protein structure and function
P-100 Alexandra Holló
The effect of the MYO16 ankyrin domain on the actomyosin system
Protein structure and function
P-101 Adrienn Skopál
The role of adenosine 2A receptor activation in the vesicular trafficking of macrophages
Protein structure and function
P-102 Rawan Abukhairan
The role of polyQ region in the RNA binding of Mixed Lineage Leukemia 4 (MLL4) protein
Protein structure and function
P-103 Julia K. Varga
Using ubiquitinated positions to gather membrane protein topology data
Protein structure and function
P-104 Dávid Kis
Acute and chronic health effects of extracellular vesicles from irradiated mice
Stem cells
P-105 Edit Hathy
CRISPR genome editing based isogenic induced pluripotent stem cell system for schizophrenia disease modeling
Stem cells
P-106 Elen Gócza
Discovery the role of MIR-302 cluster in chicken and rabbit stem cells
Stem cells
P-108 Julianna Lilienberg
Effect of microglial cells on the neurite outgrowth of human stem cell-derived neural progenitor cells
Stem cells
P-109 Dóra Reé
Establishment and characterization of DGCR8 knock-out human embryonic stem cells for modelling DiGeorge syndrome
Stem cells
P-110 Bálint Jezsó
How expression pattern of ABCG2 does change during neural differentiation?
Stem cells
P-111 Viktória Halasy
Role of CXCR4-CXCL12 signaling in colonization of developing bursa of Fabricius
Stem cells
P-112 Eszter Szabó
Stem cell-based modelling of cardiac and neuronal phenotypes in DiGeorge syndrome
Stem cells
P-113 Tamás Kovács
The role of BMP signaling and the embryonic ceca in the enteric nervous system development
Stem cells
P-114 Pál Botó
Zbtb46 mediated suppression of the embryonic stem cell derived myeloid lineage development
Stem cells
P-162 Mária Husvéth-Tóth
In vitro modelling the protective effect of rosuvastatin against doxorubicin-induced endothelial injury
Drug development
P-171 Ildikó Bódi
A new phenotype in the thymus of children operated with atrial septal defect
Molecular mechanism of diseases

Poster Session II. (P115 – P225) – Saturday, 30 March 2019

P-115 Lili Anna Kenéz
A new relationship between miniCORVET and HOPS tethering complexes
Autophagy and intracellular trafficking
P-116 Marianna Holczer
A systems biological analysis of AMPK-mTOR-ULK1 module-controlled autophagy
Autophagy and intracellular trafficking
P-117 Sarolta Tóth
C11.1 protein is a new regulator of actin network rearrangement involved in exocytosis of secretory granules
Autophagy and intracellular trafficking
P-118 Renáta Gáspár
Cardiomyocytes are protected by kynurenic acid against simulated ischemia/reperfusion injury
Autophagy and intracellular trafficking
P-119 Margita Márton
Connections between genes of PERK pathway upon endoplasmic reticulum stress
Autophagy and intracellular trafficking
P-120 Hussein Abuammar
Deciphering the role of the small GTPase Rab27 in Drosophila autophagy
Autophagy and intracellular trafficking
P-121 Erika Fodor
Developing genetic tools to study the role of autophagy in zebrafish development and tissue homeostasis
Autophagy and intracellular trafficking
P-122 Péter Nánási
Doxorubicin induces large-scale and distinct H2A and H2B redistribution in live cells
Autophagy and intracellular trafficking
P-123 Janka Szinyákovics
EDTP and MTMR14 lipid phosphatases promote brain aging by progressively downregulating autophagy throughout adulthood
Autophagy and intracellular trafficking
P-124 Zoltán Kovács
FRAP analysis of the nuclear import of the cytoskeletal Moesin protein
Autophagy and intracellular trafficking
P-125 Dalma Feil-Börcsök
Investigation of sorting nexin functions in Drosophila tissues
Autophagy and intracellular trafficking
P-126 Ármin Sőth
Investigation of the interaction of two endosomal tethering factors, Rabenosyn-5 and Vps18
Autophagy and intracellular trafficking
P-127 Dávid Tóth
Links between DNA repair proteins and autophagy regulation
Autophagy and intracellular trafficking
P-128 Asha Kiran Maddali
Lipids of autophagic membranes and their functional roles
Autophagy and intracellular trafficking
P-129 Zsófia Simon-Vecsei
Loss of Vps18 affect autophagy and cell adhesion of mammalian cells
Autophagy and intracellular trafficking
P-130 András Rubics
Rab3GAP-Rab18 module promotes autolysosome maturation through Atg14-PI3K complex
Autophagy and intracellular trafficking
P-131 Poulami Banik
The role of the autophagy machinery in glial engulfment of axon debris
Autophagy and intracellular trafficking
P-132 Zsófia Gyetvai
The role of the SNARE protein Ykt6 in crinophagy
Autophagy and intracellular trafficking
P-133 Kinga Tagscherer
Two myotubularin phosphatases, EDTP and Mtmr6, differentially regulate autophagy in Drosophila melanogaster
Autophagy and intracellular trafficking
P-134 Győző Szenci
Ykt6 acts as a non-canonical SNARE in autophagosome-lysosome fusion
Autophagy and intracellular trafficking
P-135 Péter Szikora
Analyzing the effect of splicing factor mutations with information theoretic methods
P-136 Ádám Nagy
Analyzing the prognostic value of immunomodulatory genes in multiple types of solid tumors
P-137 Torda Varga
COMPARE1K+, a bioinformatic pipeline and an R package to analyse the evolution of thousands of genomes
P-138 Ilona Tornyi
Comprehensive analysis of signal peptide prediction algorithms
P-139 Emese Tolnai
Effect of dietary fructooligosacharide (FOS), carotenoids, anthocyanins and probiotics supplementation on the intestinal microbiome in broiler chickens
P-140 Noam Makmal
Epigenetic determinants of gene expression noise in hematopoietic stem cells
P-141 Áron Bartha
Features of exceptional survivors – defining advanced stage cancer patients with prolonged overall survival
P-142 Gábor Fidler
Impact of different alterations of sample preparation, lysis protocols and DNA separation on shifts in composition of broiler chicken microbiota
P-143 Menyhart Otília
Potential new therapeutic targets in colorectal carcinoma linked to driver mutations
P-144 Zoltán Gáspári
Prediction of single α-helices in large sequence sets
P-145 Mónika Mórocz
An old player in a new role: HLTF tumour suppressor fighting shoulder to shoulder with FANCJ against replication stress
DNA repair and Carcinogenesis
P-146 Karola Almási
Analyses of the function of Saccharomyces cerevisiae Mgs1 protein in G-quadruplex replication
DNA repair and Carcinogenesis
P-147 Ádám Póti
Correlation of homologous recombination deficiency induced mutational signatures with sensitivity to PARP inhibitors and cytotoxic agents
DNA repair and Carcinogenesis
P-148 Enikő Sajben-Nagy
Development of new reporter systems to monitor the accuracy of G4 replication in Saccharomyces cerevisiae
DNA repair and Carcinogenesis
P-149 Sham Jdeed
Dissecting molecular pathways to understand breast cancer chemoprevention
DNA repair and Carcinogenesis
P-150 András Penyige
Identification of differentially-expressed miRNAs in plasma samples of ovarian cancer patients
DNA repair and Carcinogenesis
P-151 Rita Hirmondó
Investigation of the mutator effects of various genotoxic stresses provides insight into the mechanism of drug resistance development in Mycobacteria
DNA repair and Carcinogenesis
P-152 Szabó Judit Eszter
Investigation of uracil-DNA repair in Staphylococcus aureus
DNA repair and Carcinogenesis
P-153 Szilvia Juhász
PARylation and DNA accessibility during the DNA damage response
DNA repair and Carcinogenesis
P-154 Kata Dudás
Regulatory function of ZBTB1 in the DNA damage tolerance pathways
DNA repair and Carcinogenesis
P-155 Kovács Mihály
Single-molecule techniques reveal how proteins can access DNA coated by SSB proteins
DNA repair and Carcinogenesis
P-156 Dániel Molnár
The effects of genotoxic stress factors on DNA repair system in Mycobacteria
DNA repair and Carcinogenesis
P-157 Virág Székely
A novel fluorescence-based assay to characterize transporters involved in hepatic detoxification
Drug development
P-158 Orsolya Lang
Design of novel heterocyclic molecules for apoptosis induction
Drug development
P-159 Mohana Krishna Gopisetty
Endoplasmic reticulum stress: major player in size-dependent inhibition of P-glycoprotein by silver nanoparticles in multidrug-resistant breast cancer cells
Drug development
P-160 Virág Demján
Impact of Stellaria media tea lyophilizate on hypercholesterolemia in rats
Drug development
P-161 László Kőhidai
Impedance-based analysis – A dedicated technique to characterize efficacy of novel antitumour compounds
Drug development
P-162 Áthelyezve a P-I szekció végére / Moved to the end of session P-I
P-163 István Szász
New perspective in melanoma treatment – Targeting endoplasmatic reticulum stress
Drug development
P-164 Réka Laczkó-Rigó
Structural dissection of 13-epiestrones based on the interaction with the steroid transporting human Organic Anion-Transporting Polypeptide, OATP2B1
Drug development
P-165 Kuljeet Singh
The effect of sour cherry flavonoids and Anthocyanins on Pgp activity
Drug development
P-166 Dániel Gerber
Advances of bioinformatic methodology in archaeogenetics
Human genetics and archaeogenetics
P-167 Gloria Zodanu
Chromosome 22q11 copy number variations in paediatric and adult patients with congenital heart defects
Human genetics and archaeogenetics
P-168 Kornélia Tripolszki
Computational and functional analyses of angiogenin mutations identified in Hungarian patients with amyotrophic lateral sclerosis
Human genetics and archaeogenetics
P-169 Kitti Maár
Maternal lineages from 10th century commoner cemeteries of the Carpathian Basin
Human genetics and archaeogenetics
P-170 Éva Viola Surányi
A comprehensive analysis of the contribution of genotoxic stress conditions to the development of antibiotic resistance genes in Mycobacteria
Molecular mechanism of diseases
P-171 Áthelyezve a P-I szekció végére / Moved to the end of session P-I
P-172 Máté Varga
A new zebrafish model for Pseudoxanthoma elasticum (PXE)
Molecular mechanism of diseases
P-173 Orsolya Mózner
ABCG2 mutations found in gout patients have various effects on the expression of the protein
Molecular mechanism of diseases
P-174 Ádám Tiszlavicz
Acquired cellular stress resistance in the absence of heat shock protein induction
Molecular mechanism of diseases
P-175 Vince Szegeczki
Alterations of PACAP signalling in testis of Alzheimer’s disease modelling mice
Molecular mechanism of diseases
P-176 Csilla Szűcs-Somogyi
Atypical in vitro chondrogenesis upon Transient Receptor Potential Vanilloid 4 modulation
Molecular mechanism of diseases
P-177 Tomasz Poplawski
Base excision repair in Rheumatoid arthritis – a correlation of DNA repair efficiency with the BER genes polymorphisms.
Molecular mechanism of diseases
P-178 Dominika Kovács
Clinically used PARP inhibitor olaparib protects against oxidative stress-induced epithelial barrier dysfunction in vitro
Molecular mechanism of diseases
P-179 Petra Diószegi
Decorin protects cardiomyocytes against doxorubicin-induced cytotoxicity
Molecular mechanism of diseases
P-180 Márton Szabó
Diet-induced hypercholesterolemia is associated with alterations in cardiac gene expression profile
Molecular mechanism of diseases
P-181 Renáta Hamar
dkc1 mutations are associated with changes in tp53 expression and growth impairment
Molecular mechanism of diseases
P-182 Ireneusz Majsterek
Evaluation of BDNF and HSP70 gene expression in the pathogenesis of multiple sclerosis patient in Polish population
Molecular mechanism of diseases
P-183 Fanni Dóra
Gene expressional changes in the dorsomedial prefrontal cortex of suicide victims – an RNA sequencing study
Molecular mechanism of diseases
P-184 Kitti Andreidesz
Investigating the effects of a PARP inhibitor, HO-3089, on signaling pathways in monocrotaline-induced pulmonary hypertension in rat lung tissue
Molecular mechanism of diseases
P-185 Nikoletta Gálik
Investigation of the activation of certain DNA repair enzymes in Mycobacterium smegmatis under stress conditions
Molecular mechanism of diseases
P-186 János Schmidt
Lysophosphatidylcholine depletion in head and neck squamous cell carcinoma identifies MAGL and LYPLA1 as potential biomarkers
Molecular mechanism of diseases
P-187 Orsolya Biró
Maternal and fetal folate metabolism gene polymorphisms as risk factors for congenital heart disease
Molecular mechanism of diseases
P-188 Zsolt Matula
Mitochondrial exchange between myeloma cells and bone marrow stromal cells
Molecular mechanism of diseases
P-189 Gyöngyvér Orsolya Sándor
Pancreatic cancer patient-derived 3D organoids to analyze extracellular vesicles
Molecular mechanism of diseases
P-190 Sára Sándor
The role of endogenous retroelements in neural aging in the canine model of human senescence
Molecular mechanism of diseases
P-191 Ádám Sipos
The role of HCN2 in the development of ileus
Molecular mechanism of diseases
P-192 Gábor Hajdú
Toxic stress-specific molecular cytoprotective responses determine behavioural adaptation in C. elegans
Molecular mechanism of diseases
P-193 Ádám Pap
A neglected post-translational modification: extracellular O-glycosylation
P-194 Róbert Király
An attempt to identify interacting partners and substrates of transglutaminase 4
P-195 Ervin Gyenge
Analysis of salivary protein profiles in oral leukoplakia, oral lichen planus and oral squamous cell carcinoma using proteomics techniques
P-196 Katalin Kékesi
Chronic cerebral hypoperfusion induced synaptic proteomic changes in rat central nervous system
P-197 Éva Csősz
Dissecting the uteroptrophic effect of estradiol in rodents by mass spectrometry-based proteomics
P-198 Márton Gyula Milley
Effect of repeated measurements and choice of database search engines in bottom-up proteomics
P-199 Balázs Vedelek
Identification and validation of H1 interacting partners
P-200 Bálint Péterfia
Interaction of the postsynaptic scaffold proteins GKAP and Shank-1
P-201 Bella Bruszel
Investigation of serum protein biomarkers for human glioblastoma multiforme
P-202 Gábor Kecskeméti
Investigation of the effect of overexpression of different ABC transporters on the cell membrane proteome
P-203 Gábor Tóth
On-tissue digestion of prostate cancer biopsies for proteomics
P-204 Katalin Medzihradszky
Phosphorylation-dependent diversification of RETINOBLASTOMA RELATED protein complexes in Arabidopsis thaliana
P-206 Gergő Kalló
Quantitative analysis of tear proteins from patients with diabetic retinopathy with different mass spectrometry-based methods
P-207 Gitta Schlosser
Statistical investigation of citrulline effect on a citrullinome database
P-208 József Kardos
Synaptic functional disturbances leading to C1Q deposition in health and disease
P-209 Emese Tolnai
Alterations of certain microRNA expressions in fevered neutropenia patients
Regulatory RNAs
P-210 Beáta Boros-Oláh
Examination of R-loops and chromatin loops with chromatin conformation capture techniques
Regulatory RNAs
P-211 Éva Hamar
Identification of RNA interference-related genes in barley (Hordeum vulgare L.)
Regulatory RNAs
P-212 Anna Farkas
The role of lncRNAs and histone methyltransferases in epithelial-mesenchymal transition
Regulatory RNAs
P-213 Ábel Fóthi
Tissue-specific promoter usage regulates primary microRNA processing efficiency of the human Chromosome 19 MicroRNA Cluster
Regulatory RNAs
P-214 Anita Kurilla
Translation termination factor is regulated by readthrough and NMD through 3’UTR intron in N. crassa
Regulatory RNAs
P-215 András Kis
Utilization of CRISPR/Cas9 system for investigation of a potential new wheat miRNA targeting RNA polymerase V (Pol V) subunit
Regulatory RNAs
P-216 Emese Demián
Viral diagnostics of rootstock plantations and the complex pathogen elimination methods of grapevine by small RNA NGS
Regulatory RNAs
P-217 Dániel Baráth
Virome of Hungarian peach plantations identified by small RNA NGS
Regulatory RNAs
P-218 Bíborka Pillér
Cellular interactions in yeast colonies
Systems biology
P-219 Ildikó Karcagi
Generation of successive random deletions in E. coli reveals the evolutionary gains and limits of genome reduction
Systems biology
P-220 János Juhász
In-silico modelling of yeast colony growth
Systems biology
P-221 Bence Keömley-Horváth
Integrating molecular databases in a proteome-wide simulation environment
Systems biology
P-222 Nóra Molnár, Emese Nagy
Morphological characteristics of yeast colonies
Systems biology
P-223 Bertalan Kovács
Structural ensembles of PDZ tandem generated by externally restrained MD simulation
Systems biology
P-224 Walliyulahi Ajibola
The effect of local rifampicin treatment on the composition and resistance of the intestinal microbiota: the first steps taken
Systems biology
P-225 Eszter Németh
The genomic imprint of cancer therapies helps timing the formation of metastases
Systems biology
P-083 Rita Szilvia Kiss
Effect of protein aggregation on protein complex assemblies
Protein structure and function